Absolution Pure
Absolutions were a class of "fatal channels" in the I.C.E. Age mechanics or Rolemaster system. They were instant death effects, where the soul was torn from the body. Spells of Absolution Pure were irrevocable in the absence of a high-level resurrection spell, and Dark Absolution would destroy the soul itself, forever ending the existence of the target. Very old spell lists refer to the soul as "needing to exist" for this reason. In the Shadow World setting, Dark Absolutions were always the work of servants of the Unlife, and were considered the worst possible fate in the religion of Lorminstra.
Possible forms of Dark Absolution included being "ordained", falling prey to malevolent artifacts, being fed upon by dark powers, as well as black curses, such as "Kadaena's Kiss" which melted away all of the flesh and kept the skeleton alive for hours in agony before the soul was destroyed. Pale Embrace was arguably a modern spell of this kind, which was used for assassinations in Elven courts.